The PVRL2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CD112, Miscellaneous, Nectin 2, NECTIN1, NECTIN2, and PVRL2. This antibody recognizes Human antigen. The PVRL2 Antibody has been validated for the following applications: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized